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John N Weinstein Selected Research

Aspartate-Ammonia Ligase (Asparagine Synthetase)

6/2014The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.
1/2009Asparagine synthetase: a new potential biomarker in ovarian cancer.
10/2008Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
11/2006Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
4/2006Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.

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John N Weinstein Research Topics

Disease

87Neoplasms (Cancer)
10/2021 - 03/2002
8Ovarian Neoplasms (Ovarian Cancer)
01/2014 - 09/2003
7Urinary Bladder Neoplasms (Bladder Cancer)
06/2020 - 08/2007
6Breast Neoplasms (Breast Cancer)
01/2017 - 01/2007
6Colonic Neoplasms (Colon Cancer)
01/2016 - 03/2002
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2019 - 11/2006
5Carcinoma (Carcinomatosis)
11/2017 - 06/2003
4Renal Cell Carcinoma (Grawitz Tumor)
01/2017 - 05/2013
4Lung Neoplasms (Lung Cancer)
02/2016 - 01/2013
3Leukemia
01/2019 - 11/2006
3Carcinogenesis
01/2018 - 01/2008
3Glioblastoma (Glioblastoma Multiforme)
03/2015 - 07/2013
3Melanoma (Melanoma, Malignant)
04/2014 - 06/2004
3Hypoxia (Hypoxemia)
07/2006 - 07/2004
2Inflammation (Inflammations)
07/2022 - 01/2018
2Aneuploidy (Aneuploid)
12/2018 - 01/2018
2Endometrioid Carcinoma
04/2018 - 08/2013
2Glioma (Gliomas)
06/2015 - 07/2013
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2014 - 01/2013
2Neoplasm Metastasis (Metastasis)
01/2010 - 11/2008
2Chromosome Aberrations (Chromosome Abnormalities)
09/2007 - 05/2007
2Hypersensitivity (Allergy)
09/2007 - 05/2006
1Pancreatic Neoplasms (Pancreatic Cancer)
10/2021
1Myasthenia Gravis
12/2018
1Autoimmune Diseases (Autoimmune Disease)
12/2018
1Thymoma (Thymic Carcinoma)
12/2018
1sporadic Papillary renal cell carcinoma
01/2016
1Polyps
01/2016
1Adenoma (Adenomas)
01/2016
1Liver Neoplasms (Liver Cancer)
11/2015
1Endometrial Neoplasms (Endometrial Cancer)
11/2015
1Adenocarcinoma of Lung
08/2015
1Brain Neoplasms (Brain Tumor)
03/2015
1Ductal Carcinoma
10/2014
1Head and Neck Neoplasms (Head and Neck Cancer)
09/2014
1Testicular Neoplasms (Testicular Cancer)
04/2014
1Hepatocellular Carcinoma (Hepatoma)
08/2013
1Squamous Cell Carcinoma of Head and Neck
08/2013
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
08/2013

Drug/Important Bio-Agent (IBA)

23Pharmaceutical PreparationsIBA
02/2016 - 08/2002
22Proteins (Proteins, Gene)FDA Link
01/2020 - 09/2003
18RNA (Ribonucleic Acid)IBA
01/2020 - 10/2008
17DNA (Deoxyribonucleic Acid)IBA
01/2018 - 04/2006
13Messenger RNA (mRNA)IBA
01/2020 - 09/2003
12MicroRNAs (MicroRNA)IBA
01/2019 - 05/2007
12Biomarkers (Surrogate Marker)IBA
01/2016 - 03/2005
9Asparaginase (Elspar)FDA Link
01/2019 - 04/2006
6Biological ProductsIBA
12/2018 - 05/2007
6ChromatinIBA
01/2018 - 11/2008
5EnzymesIBA
01/2018 - 04/2006
5Long Noncoding RNAIBA
10/2017 - 10/2014
5Aspartate-Ammonia Ligase (Asparagine Synthetase)IBA
06/2014 - 04/2006
5OligonucleotidesIBA
04/2006 - 01/2003
5Complementary DNA (cDNA)IBA
04/2006 - 03/2002
4Phenobarbital (Luminal)FDA Link
01/2020 - 10/2015
4Small Interfering RNA (siRNA)IBA
07/2014 - 06/2004
4CamptothecinIBA
10/2010 - 03/2002
3AsparagineIBA
10/2021 - 11/2006
3Antineoplastic Agents (Antineoplastics)IBA
01/2019 - 09/2003
3Cadherins (E-Cadherin)IBA
10/2016 - 02/2007
3Transcription Factors (Transcription Factor)IBA
10/2015 - 07/2004
2GlutaminaseIBA
01/2019 - 06/2014
2Ligases (Synthetase)IBA
01/2018 - 04/2006
2Codon (Codons)IBA
01/2018 - 06/2008
2ProteomeIBA
11/2017 - 05/2014
2Protein Isoforms (Isoforms)IBA
09/2014 - 05/2013
2AntibodiesIBA
05/2014 - 04/2006
22- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
10/2010 - 03/2002
2hydrogen sulfite (bisulfite)IBA
01/2010 - 02/2007
2Cisplatin (Platino)FDA LinkGeneric
01/2008 - 03/2003
2Hydroxyurea (Hydrea)FDA LinkGeneric
09/2007 - 11/2005
2StaurosporineIBA
09/2007 - 03/2003
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
05/2006 - 12/2004
2ATP-Binding Cassette Transporters (ABC Transporters)IBA
12/2004 - 08/2004
1InterleukinsIBA
07/2022
1AutoantigensIBA
12/2018
1Transforming Growth Factors (Transforming Growth Factor)IBA
10/2018
1Transfer RNA (tRNA)IBA
01/2018
1Cancer VaccinesIBA
01/2017
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
10/2016
1B7-H1 AntigenIBA
02/2016
1Fumarate Hydratase (Fumarase)IBA
01/2016
1NucleotidesIBA
01/2016
1Transforming Growth Factor-beta Type I ReceptorIBA
01/2016
1Phosphotransferases (Kinase)IBA
10/2015
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
10/2015
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
10/2015
1Histone Deacetylase InhibitorsIBA
10/2015
1Mechanistic Target of Rapamycin Complex 1IBA
08/2015
1Erlotinib Hydrochloride (CP 358,774)FDA Link
12/2014
1Sorafenib (BAY 43-9006)FDA Link
12/2014
1Estrogen ReceptorsIBA
10/2014
1Pyruvate KinaseIBA
09/2014
1Glutamic Acid (Glutamate)FDA Link
06/2014
1Glutamine (L-Glutamine)FDA Link
06/2014
1AntigensIBA
04/2014
1Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
05/2013

Therapy/Procedure

23Therapeutics
10/2021 - 09/2003
6Drug Therapy (Chemotherapy)
01/2020 - 08/2004
2Immunotherapy
01/2017 - 04/2014